Formulation and Evaluation of Clopidogrel Bisulfate Liquisolid Compact
نویسندگان
چکیده
منابع مشابه
Formulation and Evaluation of Clopidogrel Bisulfate Immediate Release Tablets
Many patients especially children and elderly have difficulty in swallowing tablets and capsules and consequently unable to take medicine as prescribed. Almost 50% of the population is affected by such problem, resulting in the high incidence of non compliance and ineffective therapy. Most pharmaceutical forms for oral administration are formulated for direct ingestion, or for chewing, or for p...
متن کاملFormulation and Evaluation of Transdermal Drug Delivery System of Clopidogrel Bisulfate
Transdermal drug delivery is an alternative route for systemic drug delivery which minimizes the absorption and increases the bioavailability. Orally Clopidogrel bisulfate has a short elimination half-life (7-8 hrs.), low oral bioavailability (50%) undergoes extensive first pass metabolism (85%) and frequent high doses (75 mg) are required to maintain the therapeutic level as a result, dose dev...
متن کاملFormulation and Evaluation of Rofecoxib Liquisolid Tablets
The aim of our study was to improve the availability of Rofecoxib a practically insoluble non-steroidal anti-inflammatory drug, as a model drug by using liquisolid technique. The effect of powder substrate composition on the flowability and compressibility of liquisolid compacts were evaluated. Specifically, several liquisolid formulations, containing 25-mg Rofecoxib, which containing different...
متن کاملFORMULATION DEVELOPMENT AND EVALUATION OF CLOPIDOGREL FASTDISSOLVING TABLETS
The main objective of present research work is to formulate the Clopidogrel Fast Dissolving tablets. Clopidogrel, an antiplatelet drug, belongs to BCS Class-II and used to control Heart attack, Hypertension by inhibiting Platelet activation and aggregation .The Fast Dissolving tablets of Clopidogrel were prepared employing different concentrations of Crospovidone and Croscarmellose sodium in di...
متن کاملFormulation and Evaluation of Liquisolid Compacts of Carvedilol P.Sandhya
The purpose of this study is to develop a novel liquisolid technique to enhance the dissolution rate of poorly water soluble drug Carvedilol, a BCS class II drug, which is a β-blocker, by using different excipients. The main components of a liquisolid system are a non volatile solvent, carrier and coating materials and a disintegrant. Liquisolid system refers to the formulations that are formed...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512)
سال: 2018
ISSN: 1683-3597,2521-3512
DOI: 10.31351/vol27iss2pp135-149